NMN administration alleviated depression-like behavior and the liver weight
In Dec. 2019, a study shows that NMN administration alleviated depression-like behavior and the liver weight to body weight ratio in a mouse model ...
Read more
NMN has good effective on anti-alcohol and liver-protection
Chronic alcohol consumption is a significant cause of liver disease worldwide. Several biochemical mechanisms have been linked to the initiation an...
Read more
Nicotinamide mononucleotide (NMN) supplementation rescues cerebromicrovascular endothelial function and neurovascular coupling responses and improves cognitive function in aged mice
Regulation of cerebral blood flow (CBF) to neuronal activity through neurovascular coupling (NVC) plays a critical role in maintaining healthy cogn...
Read more
Ageing, neurodegeneration and brain rejuvenation
Although systemic diseases take the biggest toll on human health and well-being, increasingly, a failing brain is the arbiter of a death precede...
Read more
NMN promotes osteogenesis by regulating mesenchymal stromal cells via the SIRT1 pathway in aged bone marrowV
Mesenchymal stromal cells (MSCs) can differentiate to various cell types including osteoblasts, chondrocytes, and adipocytes. This cellular flex...
Read more
NMN attenuates brain injury after intracerebral hemorrhage by activating Nrf2/HO-1 signaling pathway
Replenishment of NAD+ has been shown to protect against brain disorders such as amyotrophic lateral sclerosis and ischemic stroke. However, whet...
Read more
Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD+ in healthy middle-aged and older adults
Nicotinamide adenine dinucleotide (NAD+) has emerged as a critical co-substrate for enzymes involved in the beneficial effects of regular calori...
Read more
Longevity In A Bottle
“I think once the world realizes that it’s possible to delay aging and keep people healthy for longer, then the resources will become available to ...
Read more